Epidemiology of enteric virus infections in children living in the Amazon region

ObjectivesTo verify the frequency of viruses causing acute gastroenteritis (AGE) in association with histo-blood group antigen (HBGA) and Rotarix™ vaccination coverage children from Amazon region.DesignFecal saliva samples were collected AGE (n = 485) respiratory infection (ARI) 249) clinical symptoms. Rotavirus A (RVA), norovirus, human adenovirus (HAdV), sapovirus (SaV) verified feces by molecular detection. Saliva used for HBGA phenotyping/FUT3 genotyping. Blood types, aspects RVA data recorded.ResultsNorovirus remained most prevalently detected cause (38%, 184/485 ARI 21.3%, 53/249). High HAdV frequencies observed (28.6%, 139/485) (37.3%, 93/249). was third prevalent virus (22.7%, 110/485 19.3%, 48/249) a low RV1 (61%, 448/734) verified. The SaV lower (7.2%, 35/485 6.8%, 17/249 ARI). Secretor susceptible to (OR 1.5, 95% CI 1.0–2.3; P 0.04) but not RVA, norovirus or infection.ConclusionsNorovirus could be considered main etiological agent AGE. No susceptibility SaV. showed slight Le (a-b-) heterogeneous SNPs on FUT3 gene.